Holding a PhD in analytical chemistry (University of Marseille, 1990), Sylvie joined the "Xenobiotics" unit (now Toxalim) in 1991. Since the creation of the AXIOM team, she has been developing and implementing sample preparation and chromatographic separation methods, coupled with mass spectrometry for targeted or semi-targeted analyses in metabolomics and exposomics. These approaches are applied to the identification and quantification of xenobiotics and their metabolites at trace levels in complex biological matrices. Sylvie is an active member of AFSEP, serving as treasurer of the South-West club, and co-organizes several annual thematic days specializing in the field of separation analytical techniques.